PT141

What Is It?

PT-141, also called Bremelanotide (generic clinical name), is a heavily modified synthetic derivative of alpha-melanocyte-stimulating hormone. It has been tested in clinical trials as a treatment for both female hypoactive sexual desire disorder and acute hemorrhage. PT-141 is an agonist for the melanocortin-4 and melanocortin-1 receptors. Research shows that it promotes sexual arousal and stimulates the immune system.

Biochemistry

PT-141 is developed from the Melanotan II peptide, which was initially tested as a sunless tanning agent, but it also was found to cause sexual arousal and spontaneous erections. Melanotan II was created to stimulate melanogenesis, the process that is responsible for skin tanning. Melanotan II was also known to suppress appetite and enhance libido, in addition, to promote skin tanning. During the phase 2B clinical trial of PT-141, it was tested on premenopausal women, and it was shown to help with hypoactive sexual arousal disorder. Just recently it has been FDA approved for HSDD and can be used off label for ED.

Benefits

1. Improved sexual performance

2. Increased sexual desire

3. Stronger erections

4. Greater arousal (up to 72 hours)

5. Enhanced energy

6. Promotes skin tanning

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